A VERY RARE COEXISTENCE: HAIRY CELL LEUKEMIA IN PATIENTS WITH SARCOIDOSIS

Nuri Karadurmus

Abstrakt


Although the coexistence of hairy cell leukemia with sarcoidosis has been reported in a few cases in the literature, in our case the patient had been diagnosed and followed about ten years with sarcoidosis and massive splenomegaly. It has been demonstrated that T helper 1 cells exist in organs influenced by sarcoidosis. These cells produce IL-2 and IFN-γ and induce a nonspecific inflammatory response and granuloma formation. Also these cytokines may play  a role in the development of Hairy Cell Leukemia (HCL).


Klíčová slova


Leukemia, Hairy Cell. Sarcoidosis.

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